To advance urologic care through computational and functional genomics:
– Deciphering mechanisms of response and resistance to therapy
– Establishing new models to define gene function and cell phenotypes
– Fostering a new generation of computational urologists
We are looking forward to growing our lab and community. If you want to learn more about our work, please reach out to us!
01.24.2024 Kate selected to present her single cell work at American Association for Cancer Research (AACR) Annual Meeting
01.19.2024 Filipe is the 2023 awardee of the BCAN Bladder Cancer Career Development Award
12.19.2023 Chris’s work selected for presentation at European Association of Urology Annual meeting in Paris
11.06.2023 Filipe promoted to Assistant Professor of Surgery, Harvard Medical School
05.31.2023 Konrad’s work presented at ASCO Annual Meeting
04.20.2023 Welcome Kate!
Here's our latest, led by Drs. Riaz Gillani & @RyanLCollins13 - we studied a type of inherited genetic event (structural variants) + risk of developing certain cancers in kids:
@DanaFarberNews @DFCIPopSci @BostonChildrens @broadinstitute @ScienceMagazine
Riaz Gillani, MD, and @RyanLCollins13 in @VanAllenLab @DanaFarber report in @ScienceMagazine that rare germline genetic abnormalities increase the risk of pediatric solid cancers, findings that could help improve treatments and screening.
➡️ https://bit.ly/3BQ04hK
Using experimental approaches in an @IOTNmoonshot funded study, @AramLyu, @VanAllenLab, @lawfong, et al. identified a subset of tumor-associated macrophages that mediate #immunotherapy resistance in metastatic castration-resistant #ProstateCancer @Nature .